{"id":9728,"date":"2024-08-13T09:14:15","date_gmt":"2024-08-13T09:14:15","guid":{"rendered":"https:\/\/sescs.es\/?page_id=9728"},"modified":"2024-08-13T09:14:15","modified_gmt":"2024-08-13T09:14:15","slug":"effectiveness-and-cost-effectiveness-of-a-multicomponent-strategy-to-implement-a-clinical-practice-guideline-and-improve-health-outcomes-in-people-with-lupus","status":"publish","type":"page","link":"https:\/\/sescs.es\/en\/effectiveness-and-cost-effectiveness-of-a-multicomponent-strategy-to-implement-a-clinical-practice-guideline-and-improve-health-outcomes-in-people-with-lupus\/","title":{"rendered":"Effectiveness and cost-effectiveness of a multicomponent strategy to implement a clinical practice guideline and improve health outcomes in people with lupus"},"content":{"rendered":"<div>\n<p><strong>Full Title:<\/strong> Effectiveness and cost-effectiveness of a multicomponent strategy to implement a clinical practice guideline and improve health outcomes in people with lupus<\/p>\n<\/div>\n<p><strong>Funded by:<\/strong> Instituto de Salud Carlos III (FIS PI15\/01377)<\/p>\n<p><strong>Granted Amount:<\/strong> \u20ac45,980.00<\/p>\n<p><strong>Duration:<\/strong> 3 years (2016-2018)<\/p>\n<p><strong>Principal Investigator:<\/strong> Mar\u00eda del Mar Trujillo Mart\u00edn<\/p>\n<p><strong>Collaborating Researchers:<\/strong> \u00cd\u00f1igo Rua-Figueroa Fern\u00e1ndez de Larrinoa, Elisa Trujillo Mart\u00edn, Jos\u00e9 Angel Hern\u00e1ndez Beriain, Laura Casas Hern\u00e1ndez, Yolanda Ramallo Fari\u00f1a, Tasmania del Pino Sede\u00f1o, Ana Mar\u00eda de Pascual y Medina, Laura Vallejo Torres, Ricardo S\u00e1nchez de Madariaga, I\u00f1aki Imaz Iglesia<\/p>\n<p><strong>Objectives:<\/strong> Evaluate the effectiveness and cost-effectiveness of a multicomponent knowledge transfer strategy for implementing a clinical practice guideline (CPG) for systemic lupus erythematosus (SLE). Secondary objectives to be achieved beforehand include: analyzing potential variations in clinical practice among professionals caring for people with SLE and their correspondence with scientific knowledge; systematically reviewing the scientific knowledge on Clinical Decision Support Systems (CDSS) integrated into electronic health records to optimize the development of the SLE-CDSS; analyzing the context and potential barriers and facilitators that could influence the implementation and adherence to the SLE-CDSS. Based on the results of these three objectives, the development of various components of the implementation strategy will be addressed.<\/p>\n<p><strong>Methodology:<\/strong><\/p>\n<ul>\n<li><strong>Design:<\/strong> Open-label, multicenter, cluster-randomized trial (hospital).<\/li>\n<li><strong>Setting:<\/strong> 4 reference hospitals from the Canary Islands Health Service.<\/li>\n<li><strong>Population:<\/strong> Patients with SLE and rheumatologists and internists responsible for their care.<\/li>\n<li><strong>Sample:<\/strong> 418 patients and 20 professionals (5 per hospital).<\/li>\n<li><strong>Randomization:<\/strong> By hospital (2 hospitals assigned to the experimental group and 2 to the control group).<\/li>\n<li><strong>Intervention for the Experimental Group:<\/strong> (educational component for professionals, SLE-CDSS integrated into the electronic health record based on the clinical practice guideline for SLE from the SNS Guidelines Program, and feedback integrated into the electronic health record).<\/li>\n<li><strong>Primary Outcome:<\/strong> Self-perceived SLE activity (SLAQ scale) and adherence to the SLE-CDSS recommendations.<\/li>\n<li><strong>Secondary Variables:<\/strong> Health-related quality of life (EQ-5D-5L); patient perception of their involvement in decision-making (SDM-Q-9); adherence to SLE-CDSS recommendations; resource utilization.<\/li>\n<li><strong>Analysis:<\/strong> Generalized linear model for primary and secondary variables, adjusted for patient severity and adherence to SLE-CDSS recommendations. All analyses will be conducted on an intention-to-treat basis. A structural equation modeling (EQS program) will be applied to test a model of causal relationships between sociodemographic and clinical patient characteristics, intervention, process variables, patient self-efficacy in managing their health, and health outcomes.<\/li>\n<\/ul>\n<p><strong>Contact Person:<\/strong> Mar\u00eda del Mar Trujillo Mart\u00edn (<a rel=\"noreferrer\">mar.trujillomartin@sescs.es<\/a>)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Full Title: Effectiveness and cost-effectiveness of a multicomponent strategy to implement a clinical practice guideline and improve health outcomes in &hellip; <\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[],"tags":[],"class_list":["post-9728","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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