{"id":10558,"date":"2025-03-28T11:42:50","date_gmt":"2025-03-28T11:42:50","guid":{"rendered":"https:\/\/sescs.es\/?p=10558"},"modified":"2025-05-14T15:49:12","modified_gmt":"2025-05-14T15:49:12","slug":"genicular-artery-embolization-knee-osteoarthritis-systematic-review","status":"publish","type":"post","link":"https:\/\/sescs.es\/en\/genicular-artery-embolization-knee-osteoarthritis-systematic-review\/","title":{"rendered":"SESCS publication: Genicular artery embolization for knee osteoarthritis: a systematic review with meta-analysis and cost-analysis"},"content":{"rendered":"

Ar\u00e1nzazu Hern\u00e1ndez-Yumar, Yadira Gonz\u00e1lez-Hern\u00e1ndez, Tasmania del Pino-Sede\u00f1o, Cristina Valc\u00e1rcel-Nazco, Aythami de Armas-Castellano, Estefan\u00eda Herrera-Ramos, Juli\u00e1n Portero Navarro, Montserrat Carmona-Rodr\u00edguez, Mar\u00eda Ximena Rojas-Reyes, Mar\u00eda M. Trujillo-Mart\u00edn<\/p>\n

ABSTRACT<\/strong><\/p>\n

Objetive<\/strong><\/p>\n

To assess the effectiveness, safety, and cost-effectiveness of genicular artery embolization (GAE) for the treatment of mild or moderate knee osteoarthritis (KO) refractory to standard treatment, and\/or severe KO in individuals not eligible for surgery.<\/p>\n

Method<\/strong><\/p>\n

We conducted a systematic review with meta-analysis, supplemented by a cost-analysis, comparing GAE and standard treatment, from the perspective of the Spanish National Health System (NHS) over a one-year time horizon. The health improvement required for GAE to be deemed cost-effective was quantified, considering a willingness-to-pay threshold of 25 000 \u20ac\/quality-adjusted life year (QALY).<\/p>\n

Results<\/strong><\/p>\n

We included two randomized controlled trials in our analysis. Pain estimates showed inconsistent results, and no significant effects were observed for overall function, health-related quality of life, or changes in the need for pain management medication. No serious complications or major adverse events were observed. GRADE quality of evidence ranged from moderate to low. No economic evaluations were identified. Our cost-analysis revealed that GAE would result in an incremental cost of \u20ac 3432.37 per patient, requiring a health improvement of 0.137 QALY per patient to be deemed a cost-effective technology.<\/p>\n

Conclusions<\/strong><\/p>\n

In summary, based on moderate to low-certainty evidence, it remains inconclusive whether there is any difference between GAE and standard treatment for KO. However, the use of GAE would increase the costs. Larger randomized controlled trials are needed to determine the effects of using GAE for chronic pain secondary to KO and, consequently, to ascertain whether this technology could potentially become cost-effective from the NHS perspective.<\/p>\n

Keywords<\/strong><\/p>\n

Genicular artery; Embolization; Knee osteoarthritis; Pain; Systematic review; Economic evaluation.<\/p>\n

You can read the full article here.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Ar\u00e1nzazu Hern\u00e1ndez-Yumar, Yadira Gonz\u00e1lez-Hern\u00e1ndez, Tasmania del Pino-Sede\u00f1o, Cristina Valc\u00e1rcel-Nazco, Aythami de Armas-Castellano, Estefan\u00eda Herrera-Ramos, Juli\u00e1n Portero Navarro, Montserrat Carmona-Rodr\u00edguez, Mar\u00eda … <\/p>\n","protected":false},"author":3,"featured_media":6868,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[229,105],"tags":[],"class_list":["post-10558","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-featured","category-news"],"yoast_head":"\nSESCS publication: Genicular artery embolization for knee osteoarthritis: a systematic review with meta-analysis and cost-analysis | SESCS<\/title>\n<meta name=\"description\" content=\"Mantente al d\u00eda de las novedades del Servicio de Evaluaci\u00f3n y Planificaci\u00f3n del Servicio Canario de la Salud (SESCS).\" 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